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Vaccine Talisman (Hypixel SkyBlock)

Vaccine Talisman

Common Accessory
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The Vaccine Talisman unlocks at Potato Collection III and is crafted from Poisonous Potatoes. Those come from fully grown crops broken with water on your Private Island (not by hand) and from Graveyard zombies.1

It upgrades into the Vaccine Ring with Arachne's Fangs, then into the Vaccine Artifact with Poison Samples.23 Poison and Venomous splash potions you throw yourself never affect you, with or without it.1

Sources

  1. Vaccine Talisman · Hypixel SkyBlock Wiki Community wiki read 2026-09-26
  2. Vaccine Ring · Hypixel SkyBlock Wiki Community wiki read 2026-09-26
  3. Vaccine Artifact · Hypixel SkyBlock Wiki Community wiki read 2026-09-26

Vaccine Talisman is a Common accessory. It is crafted from Poisonous Potato. It is used to make 1 other item. On the Auction House it goes for about 107.6 coins right now.

Vaccine Talisman
Accessory Power: +3
 
Reduces the effect of poison by 10%.
 
Works while in Accessory Bag!
COMMON ACCESSORY
Auction House price Lowest BINSold (6 h median)
01.08M2.16M3.24M4.32M 10/1610/3111/15

Accessory

Accessory Power3 Common
Coins per Accessory Power35.9

Upgrades into

Only the highest accessory of a line counts in the accessory bag.

Obtaining

Crafting Table
Poisonous PotatoBrewing Ingredient COMMONPoisonous PotatoBrewing Ingredient COMMONPoisonous PotatoBrewing Ingredient COMMONPoisonous PotatoBrewing Ingredient COMMONPoisonous PotatoBrewing Ingredient COMMONPoisonous PotatoBrewing Ingredient COMMONPoisonous PotatoBrewing Ingredient COMMONPoisonous PotatoBrewing Ingredient COMMONPoisonous PotatoBrewing Ingredient COMMON
Vaccine TalismanAccessory Power: +3 Reduces the effect of poison by 10%. Works while in Accessory Bag!COMMON ACCESSORY

Ingredients 307.8 · market 107.6 · buying saves 200.2

Unlocked by

Listings & sales

Recent sales

SoldPrice
Vaccine Talisman
8 h ago · auction
 33
Vaccine Talisman
10 h ago · BIN
 108
Vaccine Talisman
14 h ago · BIN
 22
Vaccine Talisman
14 h ago · auction
 299
Vaccine Talisman
17 h ago · auction
 50k
Vaccine Talisman
1 d ago · BIN
 109
Vaccine Talisman
1 d ago · BIN
 21
Vaccine Talisman
1 d ago · auction
 293
Vaccine Talisman
2 d ago · BIN
 22
Vaccine Talisman
3 d ago · auction
 66.1k

Craft from scratch

Cheapest way to make one: 307.8 by crafting, versus 107.6 to buy it. Each ingredient uses whichever is cheaper, buying it or crafting it.

Raw materials for the cheapest path

ItemAmountCost
Poisonous Potato9307.8

Usage

Used in crafting (1)

Market
Estimated value107.6
Confidencehigh
Sales / day3.57

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